1926 – At Yankee Stadium, Lou Gehrig and Babe Ruth hit back-to-back homers off Tiger starter Sam Gibson, and the Yankees outscore the Tigers, 13 – 9. Herb Pennock is the winner.

This Day In Baseball

On May 10, 1926 — 1926 – At Yankee Stadium, Lou Gehrig and Babe Ruth hit back-to-back homers off Tiger starter Sam Gibson, and the Yankees outscore the Tigers, 13 – 9. Herb Pennock is the winner.

Source:
Baseball Reference May 10