1927 – After blasting three home runs in a doubleheader split with the Red Sox the day before, Babe Ruth hits two more in a 12 – 10 win, giving him a record-tying 5 in 3 games. He leads Lou Gehrig 49 homers to 45.

On September 7, 1927 — 1927 – After blasting three home runs in a doubleheader split with the Red Sox the day before, Babe Ruth hits two more in a 12 – 10 win, giving him a record-tying 5 in 3 games. He leads Lou Gehrig 49 homers to 45.


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Sources:
Baseball Reference September 7
National Pastime
Retro Sheet
Hall of Fame
SABR Games Project
Replay The Game