1927 – Babe Ruth connects for a grand slam off Lefty Grove while Lou Gehrig hits No. 46 in a 7 – 4 win over the A’s. Ruth has 57 with three games to play. The grand slam is the Babe’s second in three days.

This Day In Baseball

On September 27, 1927 — 1927 – Babe Ruth connects for a grand slam off Lefty Grove while Lou Gehrig hits No. 46 in a 7 – 4 win over the A’s. Ruth has 57 with three games to play. The grand slam is the Babe’s second in three days.

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Sources:
Baseball Reference September 26
National Pastime September 27
Retro Sheet
Hall of Fame
SABR Games Project
Replay The Game