1928 – At St. Louis, Boston’s Red Ruffing smashes a 3-run homer in the 7th and pitches the Sox to a 5 – 3 win over the Browns.

On September 21, 1928 — 1928 – At St. Louis, Boston’s Red Ruffing smashes a 3-run homer in the 7th and pitches the Sox to a 5 – 3 win over the Browns.


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Sources:
Baseball Reference September 21
National Pastime September 21
Retro Sheet
Hall of Fame
SABR Games Project
Replay The Game