Nolan Ryan wins his 100th game as an Astro

On July 9 , 1988 —  Nolan Ryan wins his 100th game as an Astro, dropping the New York Mets, 6-3. Only Cy Young before him had won 100 games for two teams in two separate leagues. A four-run fifth inning is the difference as RBI singles by Glenn Davis, Buddy Bell and Billy Hatcher surround four walks. Ryan won 138 games for the California Angels in the 1970s.

Sources:

Astro Daily