Baltimore’s Hoyt Wilhelm one-hits the Yankees, 5 – 0, with Jerry Lumpe’s single in the 8th the spoiler. Switch-hitter Mickey Mantle hits righty against Wilhelm and does no better than he has been lefty. On May 28th, Wilhelm will beat the Yankees again, 5 – 0.

On May 22, 1959 — Baltimore’s Hoyt Wilhelm one-hits the Yankees, 5 – 0, with Jerry Lumpe’s single in the 8th the spoiler. Switch-hitter Mickey Mantle hits righty against Wilhelm and does no better than he has been lefty. On May 28th, Wilhelm will beat the Yankees again, 5 – 0.

Source:
Baseball Reference May 22