George “Hub” Collins, 28-year-old Brooklyn OF and leadoff batter, dies of typhoid fever after a brief illness. He had led the American Association in doubles in 1888 and the National League in runs in 1890.

On May 21, 1892 — George “Hub” Collins, 28-year-old Brooklyn OF and leadoff batter, dies of typhoid fever after a brief illness. He had led the American Association in doubles in 1888 and the National League in runs in 1890.

Source:
Baseball Reference May 21