In the first college baseball game ever played, Amherst defeats Williams College, 73 – 32 (66 – 32 by some reports) in Pittsfield, Massachusetts.

On july 1, 1859 In the first college baseball game ever played, Amherst defeats Williams College, 73 – 32 (66 – 32 by some reports) in Pittsfield, Massachusetts.

Source
Baseball Reference July 1