Starter Nolan Ryan and closer Goose Gossage pitch for the Texas Rangers in a 5 – 4 loss to Milwaukee. It marks the first time in major league history that a 300-game winner hurls in the same contest as a teammate with 300 saves.

On April 8, 1991 – Starter Nolan Ryan and closer Goose Gossage pitch for the Texas Rangers in a 5 – 4 loss to Milwaukee. It marks the first time in major league history that a 300-game winner hurls in the same contest as a teammate with 300 saves.

Source
Baseball Reference April 8