The Alou brothers and Orlando Cepeda lead an 18-hit attack as San Francisco overpowers the Cubs, 14 – 1. Dick Ellsworth gives up six runs in the 1st without retiring a batter. Cepeda hits two homers and a double and drives in five runs, while Felipe Alou hits his first grand slam and brother Matty Alou his first major league homer. Matty will combine with Jesus Alou in 1965 to homer in the same game. Mike McCormick is the easy winner.

On May 15, 1961 — The Alou brothers and Orlando Cepeda lead an 18-hit attack as San Francisco overpowers the Cubs, 14 – 1. Dick Ellsworth gives up six runs in the 1st without retiring a batter. Cepeda hits two homers and a double and drives in five runs, while Felipe Alou hits his first grand slam and brother Matty Alou his first major league homer. Matty will combine with Jesus Alou in 1965 to homer in the same game. Mike McCormick is the easy winner.

Source:
Baseball Reference May 15