The Buffalo Bisons hit five home runs in one inning against the Albany Senators. A rookie, Jake Plummer, is beaned by the Albany pitcher after the 5th home run in a row, and a promising career is ruined.

On May 15, 1934 — The Buffalo Bisons hit five home runs in one inning against the Albany Senators. A rookie, Jake Plummer, is beaned by the Albany pitcher after the 5th home run in a row, and a promising career is ruined.

Source:
Baseball Reference May 15