The Mariners defeat the Devil Rays, 8 – 4, as OF Rickey Henderson hits a leadoff home run for the second consecutive game, and for the 77th time in his career.

On May 21, 2000 — The Mariners defeat the Devil Rays, 8 – 4, as OF Rickey Henderson hits a leadoff home run for the second consecutive game, and for the 77th time in his career.

Source:
Baseball Reference May 21