The White Sox top the Tigers, 10 – 6. Jermaine Dye and Paul Konerko hit back-to-back homers in the 2nd for the Sox, each of them reaching 300 career home runs with their blows. No teammates had ever reached 300, 400 or 500 in the same game, let alone the same inning.

This Day In Baseball

On April 13, 2009 – – The White Sox top the Tigers, 10 – 6. Jermaine Dye and Paul Konerko hit back-to-back homers in the 2nd for the Sox, each of them reaching 300 career home runs with their blows. No teammates had ever reached 300, 400 or 500 in the same game, let alone the same inning.

Source:
Baseball Reference April 13