1949 – The Red Sox, winners of 16 out of the last 19 with the Senators, win the opener in Washington, 6 – 4.

This Day In Baseball

On September 27, 1949 — 1949 – The Red Sox, winners of 16 out of the last 19 with the Senators, win the opener in Washington, 6 – 4.

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Sources:
Baseball Reference September 27
National Pastime September 27
Retro Sheet
Hall of Fame
SABR Games Project
Replay The Game