On May 20, 2000 — After being released earlier in the month by the Mets for not hustling, Rickey Henderson, in his initial at-bat for the Mariners, hits his record 76th career leadoff home run, a shot off Esteban Yan in the team’s 4-3 loss to Tampa Bay at Safeco Field. With the round-tripper, the future Hall of Fame outfielder joins Ted Williams and Willie McCovey as the third major leaguer to have homered in four different decades.

Sources:
National Pastime

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