Cubs OF Sammy Sosa hits three home runs in a game for the second time in two weeks as he leads Chicago to a 16 – 3 win over the Brewers. Sosa is removed from the game following his home run in the 6th inning, missing a chance to tie the major league single-game mark of 4.

On August 22, 2001 — Cubs OF Sammy Sosa hits three home runs in a game for the second time in two weeks as he leads Chicago to a 16 – 3 win over the Brewers. Sosa is removed from the game following his home run in the 6th inning, missing a chance to tie the major league single-game mark of 4.

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Sources:
Baseball Reference August 22
National Pastime August 22
Retro Sheet
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