On November 3, 1965 — During a winter league game, A’s pitcher Lew Krausse strikes out a record 21 Lara batters, tossing a one-hitter for Caracas. The right-hander will average 5.1 strikeouts per nine innings during his dozen years in the major leagues, which will also include stops with the Brewers, Red Sox, Cardinals, and Braves.
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Sources:
Baseball Reference November 3
National Pastime November 3
Retro Sheet
Hall of Fame
SABR Games Project