For the first time in seven tries, the San Francisco Giants win at Pacific Bell Park as San Francisco becomes the first major league franchise to lose six games to start a season in a newly-constructed ballpark. Barry Bonds’ 8th-inning home run proves to be the difference in a 2 – 1 victory over the Montreal Expos.

On April 29, 2000 — For the first time in seven tries, the San Francisco Giants win at Pacific Bell Park as San Francisco becomes the first major league franchise to lose six games to start a season in a newly-constructed ballpark. Barry Bonds’ 8th-inning home run proves to be the difference in a 2 – 1 victory over the Montreal Expos.

Source
Baseball Reference April 29