On July 26, 1961 — Johnny Blanchard ties a major-league record by hitting his 3rd and 4th home runs in four at bats over three games. He drives in four of the Yankee runs in a 5 – 2 victory over the White Sox at Yankee Stadium. New York manages just six hits but four are homers, including one by Mickey Mantle following Blanchard’s 1st-inning clout. Blanchard will end the year with 21 homers in 243 at bats, the first player in history to hit 20 or more in fewer than 250 at bats.

Source:
Baseball Reference July 26