Minnesota’s Lenny Green and Vic Power hit back-to-back home runs off Cleveland’s Jim Perry to start the game, tying a major league record. Cleveland comes back to win, 9 – 4. It will be another nine years before two leadoff batters in the American League belt homers, and it will be Perry teeing up those as well.

On May 10, 1962 — Minnesota’s Lenny Green and Vic Power hit back-to-back home runs off Cleveland’s Jim Perry to start the game, tying a major league record. Cleveland comes back to win, 9 – 4. It will be another nine years before two leadoff batters in the American League belt homers, and it will be Perry teeing up those as well.

Source:
Baseball Reference May 10