On September 21, 1957 — The Cardinals tie a record by using 8 pitchers in one game, but lose, 9 – 8, in 10 innings to the Redlegs and slip 5 games off the pace. Jerry Lynch’s 8th-inning homer ties the game; the Redlegs set the National League mark with their 11th pinch-hit home run of the year.
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Sources:
Baseball Reference September 21
National Pastime September 21
Retro Sheet
Hall of Fame
SABR Games Project
Replay The Game