On April 30, 1961, Willie Mays of the San Francisco Giants hits four home runs against the Milwaukee Braves. Maysā outburst helps the Giants to a 14-4 win. The future Hall of Fame outfielder becomes the ninth player in major league history to hit four homers in one gameā¦The San Francisco slugger is left on deck in the top of the ninth when the third out is made by the visiting Giants.