Willie Mays hit the most home runs at San Francisco’s Seals Stadium (32), followed by Orlando Cepeda (26), Leon Wagner (13), Willie Kirkland (12), and Daryl Spencer (11).Willie Mays hit the most home runs at San Francisco's Seals Stadium (32), followed by Orlando Cepeda (26), Leon Wagner (13), Willie Kirkland (12), and Daryl Spencer (11).