With new U.S. President Warren G. Harding, former president Woodrow Wilson, and VP Calvin Coolidge watching, the Washington Senators lose their home opener, 6 – 3, to the Boston Red Sox. Senators pitcher Walter Johnson leaves after four innings, the first time he has failed to finish an Opening Game.

On April 13, 1921 – – With new U.S. President Warren G. Harding, former president Woodrow Wilson, and VP Calvin Coolidge watching, the Washington Senators lose their home opener, 6 – 3, to the Boston Red Sox. Senators pitcher Walter Johnson leaves after four innings, the first time he has failed to finish an Opening Game.

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