The Pirates suffer the most lopsided loss in team history, falling 20 – 0 to the Brewers, who complete a three-game sweep in which they outscored Pittsburgh 36 – 1. Milwaukee collects 25 hits; Ryan Braun, Prince Fielderand George Kottaras go deep, for the benefit of Randy Wolf.

On April 22, 2010 — The Pirates suffer the most lopsided loss in team history, falling 20 – 0 to the Brewers, who complete a three-game sweep in which they outscored Pittsburgh 36 – 1. Milwaukee collects 25 hits; Ryan Braun, Prince Fielderand George Kottaras go deep, for the benefit of Randy Wolf.

Source
Baseball Reference April 22

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